Cefoperazon + Sulbaktam (1:1)
Antibiotics (group of linkosamides)
Cefoperazon sodium - a semisynthetic cephalosporin antibiotic with broad-spectrum, parenteral-only action. Acts on sensitive organisms during their active reproduction by inhibiting the biosynthesis of cell wall mucopeptide.
Sulbactam sodium - a derivative of the basic penicillin nucleus. Is an irreversible inhibitor of beta-lactamases and is intended for parenteral use. The chemical structure is sodium penitsillinat sulfone.
Infectious - inflammatory diseases caused by microorganisms susceptible to the drug, disease of the upper and lower respiratory tract infections, urinary tract, peritonitis, cholecystitis and other abdominal infections, sepsis, meningitis, skin and soft tissue infections of the pelvic organs.
Prevention of infectious complications after abdominal, gynecological, cardiovascular and orthopedic surgeries.
Given the wide range of action of the drug, is effective for most infections monotherapy.
From the digestive system: the most frequently observed dysfunction of gastrointestinal diarrhea, sometimes nausea and vomiting, pseudomembranous colitis.
Allergic reactions: there were maculopapular rash, urticaria, their risk for the appearance of higher in patients with allergic predisposition.
From the body as a whole: headache, fever, pain on injection, chills.
Allergic to penicillins, sulbactam, Novoperazon or any other cephalosporins.
Solution of the drug and aminoglycosides should not be mixed directly, given the physical incompatibility between them. If conducted drug and combination therapy with aminoglycosides, the two drugs are administered by infusion using serial separate secondary catheters, catheters and primary washed adequate solution between doses of drugs. The intervals between drug administration and aminoglycosides during the day should be as long as possible. Use lactated Ringer's solution for the initial dissolution of the powder should not be, given the incompatibility of the mixture. However, compatibility can be achieved through a two-step preparation of the solution: the original powder is dissolved in water for injection and then diluted lactated Ringer's solution. Use 2% Lidocaine-NOVO for the initial dissolution of powder is not recommended because of their incompatibility. However, compatibility can be achieved through a two-step preparation of the solution: the original powder is dissolved in water for injection and then diluted with 2% Lidocaine-NOVO .
In patients treated with beta-lactam antibiotics including cephalosporins, describes cases of serious hypersensitivity reactions, sometimes leading to death. The risk for these reactions is higher in patients with a history of hypersensitivity reactions to various allergens. If you experience an allergic reaction to remove the drug and assign adequate therapy. When severe anaphylactic reactions to emergency administration of adrenalin. In severe biliary obstruction, severe liver disease, and renal failure, combined with any of these conditions, it may be necessary to adjust the dosage of the drug. In patients with impaired liver and renal function associated to monitoring serum concentrations of Novoperazon and correction of the dose if necessary. During prolonged therapy should regularly monitor the performance of the functions of internal organs, including the kidney, liver and blood system. During the period of drug treatment should avoid alcohol because may develop an effect similar to the action of disulfiram (abdominal cramps, nausea, vomiting, headache, hypotension, dyspnea, tachycardia).
Powder for preparation of an injection solution in vials of 1.0g
In protected from light place at the temperature not exceeding 25°C
Apply on doctor's orders.