Active factor (INN – International Non-proprietary Name)

Lincomycin (in the form of lincomycin hydrochloride)


Code ATC: J01FF02


Pharmacotherapeutic group

Antibiotics (group of linkosamides)


Pharmacological properties

In therapeutic doses, antibiotic acts as bacteriostatic. At higher concentrations it has a bacterial effect. It inhibits protein synthesis in microbial cell. It is ctive mainly against gram-positive cocci. It is effective against staphylococci, resistant to penicillin, tetracyclines, chloramphenicol, streptomycin, cephalosporins.
Resistance to lincomycin develops slowly.


Indications for use

Bacterial infections, caused by susceptible microorganisms (mainly staphylococci and streptococci, especially by microorganisms, resistant to penicillins, and in allergy to penicillins): acute and chronic osteomyelitis (due to the fact that lincomycin is accumulated in bone tissue, it is one of most effective drug for treatment acute and chronic osteomyelitis and other infections of bones and joints), sepsis, subacute bacterial endocarditis, chronic pneumonia, lung abscess, pleural empyema, pleuritis, otitis, purulent synovitis, postoperative suppurative complications, wound infection, skin and soft tissue infections (pyogenic dermatitis, furunculosis, phlegmon, erysipelas).


Pharmaceutical form

30% solution for injection, in ampoules of 1 ml and 2 ml.



Local anaesthetic drugs
Nootropic drugs
Antihypertensive drugs
Drugs for a parenteral food
Medicines applied at poisonings and intoxications
Medicines for metabolic processes correction
Medicines for peripheric blood circulation
Mineral drugs, microcells
Salt solutions
Analgesic and antispasmodic drugs
Nonsteroidal anti-inflammatory drugs